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Cannabinoids

Full Spectrum vs Broad Spectrum vs CBD Isolate

Which extract type is for what.

Updated 6 min read

Line illustration of a molecule

The difference between the three is how much of the plant survives processing.

TypeWhat it containsTHC
Full spectrumThe plant's whole cannabinoid and terpene profileTrace amounts below the legal threshold
Broad spectrumCannabinoids and terpenes with THC removedNone detectable
IsolatePurified cannabidiol, around 99%None

The entourage effect

The idea that cannabinoids and terpenes interact, and that the whole plant behaves differently from an isolated compound, is known as the entourage effect. It was put forward in 1998 by Ben-Shabat and Mechoulam and has been studied since.

Where it stands today matters: the hypothesis has preclinical support but is not established as a proven effect in humans, and it is not a basis for a health claim. So we describe it as a hypothesis, not as a product advantage.

When each makes sense

Picture one and the same 20% / 2000 mg bottle, made three different ways:

In a 0.5 ml servingFull spectrumBroad spectrumIsolate
CBD100 mg100 mg100 mg
Other cannabinoidsCBG, CBC, CBN — tracesCBG, CBC, CBN — tracesNone
THCBelow the legal threshold, not zeroNone detectableNone
TerpenesRetainedPartly retainedNone
Before a drug testNot the first choiceSuitableSuitable

Look at the first row: it is the same number in all three columns. None of the three is inherently "stronger" — strength comes from the milligrams in a serving, and how to work that out is in How to Choose Your First CBD Oil.

Sources & references

Every factual statement above rests on the documents listed. Check them yourself.

  1. Ben-Shabat S. et al. An entourage effect. Eur J Pharmacol, 1998https://pubmed.ncbi.nlm.nih.gov/9721036/
  2. Russo E.B. Taming THC: potential cannabis synergy. Br J Pharmacol, 2011https://pubmed.ncbi.nlm.nih.gov/21749363/
  3. Regulation (EC) No 1924/2006 on health claimshttps://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX%3A32006R1924
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